• Fact Checked
  • March 11, 2026
  • 12 min read

Bacterial Vaginosis in Pregnancy: Common, Often Silent, and Worth Taking Seriously

Table of Contents
  1. 1. What Is Bacterial Vaginosis?
  2. 2. How Common Is BV During Pregnancy?
  3. 3. Causes and Risk Factors
  4. 4. Symptoms of BV During Pregnancy
  5. 5. Impact on Pregnancy and Baby
  6. 6. Treatment of Bacterial Vaginosis During Pregnancy
  7. 7. Self-Care, Prevention, and Reducing Recurrence
  8. 8. When to Seek Care

Key Takeaways

  • BV is the most common vaginal infection during pregnancy, affecting an estimated 10–30% of pregnant women. Because most cases have no symptoms, it often goes undetected without screening.
  • Untreated BV during pregnancy carries real risks, including preterm delivery, low birth weight, and increased susceptibility to STIs.
  • Safe, effective treatment options exist. Antibiotics approved for use during pregnancy can clear BV without harming your baby, and supporting your vaginal microbiome before, during, and after treatment can help reduce recurrence.

Pregnancy affects more than most people realize. It’s a full-body change, affecting your appetite, mood, energy levels, and even your vaginal microbiome.1 Shifting hormone levels and altered immune responses can ultimately shift your vaginal pH, making you more susceptible to vaginal infections, including bacterial vaginosis.

Despite being one of the most common infections during pregnancy, BV can be tricky to catch without explicit testing because it often has no symptoms at all, so many women don't know they have it.2 But just because you don’t have symptoms doesn’t mean there isn’t risk. Untreated BV during pregnancy is associated with serious complications, including preterm birth and low birth weight. The good news is that it's diagnosable, treatable, and — with the right habits — preventable.

This post is for informational purposes only and does not constitute medical advice. See full disclaimer below.

What Is Bacterial Vaginosis?

 

An educational infographic titled "What is Bacterial Vaginosis?" explaining that it is a vaginal infection caused by a microbiome imbalance, often appearing without symptoms.

 

Bacterial vaginosis (BV) is a vaginal infection caused by an imbalance in the vaginal microbiome.3 More specifically, something has occurred that led to a drop in protective Lactobacilli bacteria and an overgrowth of harmful anaerobes. For many women, that “something” is pregnancy and the hormone shifts that accompany it.

BV is not exclusively considered a sexually transmitted infection (STI), though being sexually active is a risk factor.4 While untreated BV can develop into complications like pelvic inflammatory disease (PID) at any age, the stakes of leaving it untreated are higher than at other times in life, which is why understanding it matters.

How Common Is BV During Pregnancy?

BV is the most common cause of vaginitis in women of reproductive age.5 You don’t have to be pregnant (or even sexually active) to get it, though BV is surprisingly prevalent among pregnant women.

Studies estimate that bacterial vaginosis affects between 10% and 30% of pregnancies, though prevalence varies by population.6 It is more commonly diagnosed in the first and second trimester, when hormonal changes are most pronounced, and the vaginal environment is experiencing greater fluctuation.

As high as this number is, it could even be low. Because the majority of BV cases are asymptomatic, prevalence is likely underestimated.7 Oftentimes, it’s only caught through routine screening and prenatal testing, not because women are complaining of symptoms.

Causes and Risk Factors

 

Infographic titled "What causes BV during pregnancy?" listing six contributing factors, including hormonal shifts, douching, sexual activity, and smoking.

 

BV occurs when there’s been a disruption to the levels of protective bacteria in the vagina that allows harmful bacteria to come in, outcompete, and eventually overtake the microbiome.8

Your risk of BV is naturally elevated during pregnancy, since hormonal changes naturally shift vaginal pH and alter the composition of vaginal fluid, which can make this imbalance more likely.9 But several additional risk factors can further increase your risk, including:

  • Vaginal douching. This is one of the most consistent and modifiable risk factors for BV at any life stage. Douching disrupts the natural vaginal environment and wipes out protective bacteria.
  • Sexual behaviors, including multiple sex partners, a new partner, or unprotected sex, all of which introduce new bacteria to the vaginal environment. Women with a history of BV may still want to consider condom use even during pregnancy.
  • Smoking has been linked to altered vaginal flora and increased BV risk (and is worth avoiding during pregnancy for many other reasons too!)
  • Increased body mass index (BMI). Obesity is associated with higher BV prevalence
  • IUD use prior to conception is associated with higher BV rates, though this is more relevant pre-pregnancy
  • Concurrent sexually transmitted infections. An existing STI like chlamydia can compromise the vaginal environment's natural defenses

Some women are also at higher risk of serious pregnancy complications if they develop BV.10 These include women with:

  • A history of preterm delivery. Prior preterm birth is one of the strongest predictors of BV-related complications in a subsequent pregnancy
  • Multifetal gestation aka carrying more than one baby. This already increases the risk of preterm delivery, and BV compounds that risk further
  • Cervical insufficiency. A weakened cervix combined with a BV infection creates a particularly elevated risk for preterm delivery

It's also worth noting that research consistently shows higher rates of BV and BV-related pregnancy complications among African American women, a disparity that is not biological in origin but reflects the real health consequences of systemic racism, chronic stress, and unequal access to quality healthcare.11

Across all populations, barriers to prenatal care, including cost, insurance gaps, and geographic access, also mean that BV often goes unscreened and untreated in women who would benefit most from early intervention.

Symptoms of BV During Pregnancy

 

A comparison infographic titled "What's the difference between pregnancy discharge & BV discharge?" highlighting differences in color, odor, and physical symptoms.

 

The symptoms of BV during pregnancy are the same as at any other time, but the catch is that most cases are asymptomatic.12 When symptoms of BV do occur, they typically include:

  • Thin, watery discharge that is white, gray, or off-white (pregnancy comes with increased discharge, but BV-related discharge feels different from this)
  • Fishy vaginal odor, most noticeable after sex
  • Itching in the vulvovaginal area
  • Burning when urinating
  • Pain during sex

If you notice any of these changes, don't dismiss them as just another weird pregnancy quirk. Make an appointment with your gynecologist or midwife, even if it’s outside your prenatal appointment.

The other thing to remember is that the absence of symptoms doesn't mean the absence of infection.13 BV can be completely silent and still affect your pregnancy, increasing your risk of preterm delivery, low birth weight, and other complications without giving you a single warning sign. This is one of the most important reasons to attend every prenatal appointment, even when you feel fine (and even though there are a lot of them!). Routine screening is often the only way BV gets caught in time to treat it.

Impact on Pregnancy and Baby

 

Educational infographic titled "How untreated BV can impact pregnancy" listing five major risks including preterm delivery, miscarriage, and postpartum infection.

 

BV is associated with a range of serious complications that can affect both mother and baby, including:

  • Preterm delivery and preterm labor. This is the most significant risk associated with BV in pregnancy. BV-associated bacteria can ascend from the vagina to the uterus, triggering inflammation that initiates early labor
  • Preterm premature rupture of membranes (preterm PROM) or early breaking of the amniotic sac before labor begins
  • Miscarriage, particularly in the second trimester
  • Endometritis which is a postpartum infection of the uterine lining
  • Increased risk of acquiring STIs and STDs, including chlamydia and gonorrhea, which carry their own pregnancy complications
  • Pelvic inflammatory disease (PID), though this is more commonly associated with untreated BV outside of pregnancy
  • Low birth weight and small for gestational age, which are both associated with preterm delivery driven by BV
  • HIV-exposed uninfected infants. In women with HIV, BV increases viral shedding and transmission risk

You know that at Happy V, we aren’t about scare tactics but about the real, hard science. And we want to tell you these risks so you are better informed. Because they’re real, not hype! The connection between BV and preterm birth is one of the most well-studied in obstetrics. It's a significant reason why BV in pregnancy is taken seriously as a clinical concern and why treatment, even for asymptomatic cases identified through screening, is recommended for women at high risk of preterm delivery.14

Treatment of Bacterial Vaginosis During Pregnancy

The good news is that bacterial vaginosis is highly treatable during pregnancy using antibiotics that are safe for your baby.15 You may see concerns about congenital malformations from metronidazole use, particularly in the first trimester, floating around on the internet, but the truth is, these claims have not been supported by the weight of current evidence. That being said, your provider may choose to delay treatment until after the first trimester, but that’s going to be on a case-by-case basis, and you should always voice your concerns about any treatment plan, whether you’re pregnant or not.

Treatment options for BV during pregnancy include:

  • Oral metronidazole. This is the most commonly prescribed treatment for BV during pregnancy, typically taken twice daily for 7 days.16 It is effective, widely available, and endorsed by both the CDC and ACOG. Some women experience gastrointestinal upset with oral metronidazole. If this is a concern (or you are already struggling with issues like morning sickness), your provider may suggest an alternative.
  • Oral clindamycin. This is another first-line option, typically prescribed for 7 days and considered safe during pregnancy.17
  • Vaginal metronidazole gel (intravaginal metronidazole therapy). This is an option for women who experience significant gastrointestinal side effects from oral medication, though some guidelines prefer a more systemic treatment (think: oral antibiotic over topic gel) during pregnancy to address bacteria that may have ascended above the vaginal canal.18
  • Clindamycin cream (intravaginal clindamycin 2% vaginal cream).19 This may also be used, though some research suggests intravaginal clindamycin is less effective at reducing preterm birth risk than oral treatment.

What about treating BV without antibiotics during pregnancy?

Outside of pregnancy, some women explore non-antibiotic options like boric acid suppositories or probiotics for BV management.20 During pregnancy, these should not replace antibiotic treatment when BV is confirmed. Not only is boric acid not recommended during pregnancy, but the stakes are too high. Probiotics can be a supportive complement to antibiotic treatment, but should not be a substitute for it, especially when pregnant.

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Can BV Clear Up on Its Own During Pregnancy?

Sometimes BV resolves without treatment, but this “wait and see” game just isn’t safe if you’re pregnant.21 During pregnancy, the risks of leaving BV untreated, especially for women at high risk of preterm delivery, generally outweigh any benefit to waiting. If your provider has confirmed BV during pregnancy, treatment is the right next step.

Can You Have a Healthy Pregnancy After BV Treatment?

Yes, absolutely. Treating BV with antibiotics during pregnancy does not harm the baby and can actually improve pregnancy outcomes by reducing the risk of preterm delivery and related complications.22 Many women successfully treat BV and go on to have full-term, healthy pregnancies. The key is treating it promptly and following your provider's guidance.

Self-Care, Prevention, and Reducing Recurrence

 

A pregnant person during a medical checkup with a text box advising to avoid douching, use condoms, and attend prenatal appointments to screen for "silent BV."

 

BV has a high recurrence rate even after successful antibiotic treatment.23 If you’ve had BV while pregnant or had frequent infections before conception, consider risk reduction an important part of your prenatal care, just like taking a daily prenatal vitamin.

The best ways to prevent BV during pregnancy are:

  • Don't douche. Vaginal douching is one of the most consistent risk factors for BV and should be avoided entirely during pregnancy (and in general).
  • Use condoms. Condoms aren’t just about not getting pregnant. Consistent condom use during pregnancy reduces exposure to bacteria that can disrupt vaginal pH and lead to BV.
  • Limit sex partners. Reducing the number of sex partners limits exposure to unfamiliar microbiomes.
  • Avoid scented products near the vagina, including soaps, wipes, and sprays. These get their scents through chemicals that can disrupt your microbiome.
  • Don't smoke. Smoking is a modifiable risk factor for BV (and also carries its own significant pregnancy risks).
  • Attend all prenatal appointments. Regular prenatal care is your best tool for catching BV early, especially in asymptomatic cases.

Supporting Your Vaginal Microbiome During Pregnancy

While antibiotics are an important tool to clear an active BV infection, they disrupt the broader vaginal microbiome in the process.25 They kill off the protective Lactobacilli bacteria along with the infection-causing bacteria, which is part of why recurring bacterial vaginosis is so common.

One of the ways you can curb this disruption is by taking a daily probiotic during and in the weeks following a course of antibiotics, particularly a targeted vaginal probiotic made with strains of Lactobacillus shown to improve overall vaginal health.

Happy V's Prebiotic + Probiotic is doctor-formulated with clinically studied Lactobacillus strains specifically chosen to support vaginal health and restore healthy vaginal flora.

While it won't treat an active BV infection, it can be a meaningful part of your pregnancy and postpartum care routine, as preclinical studies have shown it to be effective in reducing the growth of Gardnerella vaginalis, the bad bacteria behind most BV infections. Though it’s made with no fillers, GMOs, or other harmful ingredients, it’s always best to check with your healthcare provider before starting any new supplement during pregnancy.

When to Seek Care

Given how often bacterial vaginosis is asymptomatic, routine screening is the only reliable way to catch it. Especially if you have a history of BV, don’t wait for symptoms to show up. Discuss the risk with your doctor proactively in your early prenatal appointments.

It’s also okay and often necessary to see your doctor outside of your scheduled prenatal appointments, especially if:

  • You notice unusual vaginal discharge, fishy odor, itching, or burning
  • You have a history of preterm delivery or other high-risk pregnancy factors
  • Your symptoms persist or return after completing a course of antibiotics
  • You have a confirmed or suspected STI alongside your symptoms
  • You're unsure whether what you're experiencing is normal pregnancy discharge or something that needs evaluation

Keep the Conversation Going

 

Disclaimer: This blog is for informational and educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Statements about supplements have not been evaluated by the Food and Drug Administration. For more information about vaginal infections, visit the CDC or speak to a licensed healthcare provider.

FAQ

What is bacterial vaginosis and why is it a concern during pregnancy?

Bacterial vaginosis (BV) is an imbalance of vaginal bacteria that can occur during pregnancy. Even when it causes few or no symptoms, untreated BV can increase the risk of certain complications for both mother and baby.

How can bacterial vaginosis affect pregnancy outcomes?

BV during pregnancy has been linked to a higher risk of preterm birth, low birth weight, and post-delivery infections. Addressing it early can help reduce these potential complications, which is why it's important to attend all prenatal appointments and screenings.

What are common signs of bacterial vaginosis in pregnant women?

Many pregnant women with BV have no symptoms at all. Those who do may notice unusual discharge, an unpleasant odor, itching, or irritation. Because BV is often asymptomatic, regular prenatal screenings are important for detection. Even asymptomatic BV can cause complications.

When should a pregnant woman seek medical attention for possible bacterial vaginosis?

Reach out to your healthcare provider if you notice any changes in vaginal discharge (either color, consistency, or smell) or if you experience itching or discomfort. Early detection and treatment can help protect both maternal and fetal health.

Why is regular screening important for vaginal health during pregnancy?

Because BV often has no noticeable symptoms, regular screening is the most reliable way to catch it early. Timely treatment can help prevent complications associated with untreated vaginal infections during pregnancy.

How do you treat BV while pregnant?

BV during pregnancy is most commonly treated with oral metronidazole or oral clindamycin for 7 days, though there are other options, too. Your healthcare provider will recommend the best option based on your symptoms, trimester, and risk factors. Do not (DO NOT) attempt to self-treat BV during pregnancy without medical guidance.

Does BV clear up on its own during pregnancy?

Possibly, but it's not worth the risk. During pregnancy, untreated BV is linked to preterm delivery, low birth weight, and other serious complications. If BV is confirmed during pregnancy, treatment is strongly recommended.

How can I prevent BV during pregnancy?

Avoid douching, use condoms consistently, limit sex partners, avoid scented products near the vagina, don't smoke, and keep up with prenatal care so that asymptomatic BV can be caught through screening.

Can I take BV antibiotics and still have a healthy pregnancy?

Absolutely. The antibiotics used to treat BV during pregnancy (namely, metronidazole and clindamycin) are considered safe and are endorsed by the CDC and ACOG. Treating BV can actually improve pregnancy outcomes by reducing the risk of preterm delivery.

How do I cure BV without antibiotics during pregnancy?

During pregnancy, antibiotics are the recommended treatment for confirmed BV. There's no natural remedy that adequately substitutes for them when the stakes are this high. That said, probiotics can be a great complement to antibiotic treatment, helping restore vaginal flora after your course is complete. Just don't use them in place of the antibiotics your provider prescribed.

[1] DuPont HL, Salge MMH. The Importance of a Healthy Microbiome in Pregnancy and Infancy and Microbiota Treatment to Reverse Dysbiosis for Improved Health. Antibiotics (Basel). 2023;12(11):1617. Published 2023 Nov 11. doi:10.3390/antibiotics12111617

[2] Muzny CA, Schwebke JR. Asymptomatic Bacterial Vaginosis: To Treat or Not to Treat?. Curr Infect Dis Rep. 2020;22(12):32. doi:10.1007/s11908-020-00740-z

[3] Carlson K, Mikes BA, Garg M. Bacterial Vaginosis. [Updated 2025 Nov 7]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-.

[4] Abou Chacra L, Ly C, Hammoud A, et al. Relationship between Bacterial Vaginosis and Sexually Transmitted Infections: Coincidence, Consequence or Co-Transmission?. Microorganisms. 2023;11(10):2470. Published 2023 Oct 1. doi:10.3390/microorganisms11102470

[5] Cleveland Clinic. Bacterial vaginosis (BV). Cleveland Clinic. Updated February 6, 2023. Accessed March 2026.

[6] Djogic LM, Cehic E, Hodzic H, Babic A, Sljivo B. Prevalence of Bacterial Vaginosis of Pregnant Women in the General Hospital Tesanj. Med Arch. 2025;79(3):194-198. doi:10.5455/medarh.2025.79.194-198

[7] Achondou AE, Fumoloh FF, Aseneck AC, Awah AR, Utokoro AM. Prevalence of bacterial vaginosis among sexually active women attending the CDC Central Clinic Tiko, South West Region, Cameroon. Afr J Infect Dis. 2016;10(2):96-101. doi:10.21010/ajid.v10i2.4

[8] Chen X, Lu Y, Chen T, Li R. The Female Vaginal Microbiome in Health and Bacterial Vaginosis. Front Cell Infect Microbiol. 2021;11:631972. Published 2021 Apr 7. doi:10.3389/fcimb.2021.631972

[9] Danjuma FY, Dashen MM, Ngene AC, Egbere OJ. Prevalence of bacterial vaginosis and its associated risk factors among women of reproductive age attending Jos University Teaching Hospital, Plateau State, Nigeria. GMS Hyg Infect Control. 2025;20:Doc51. Published 2025 Sep 22. doi:10.3205/dgkh000580

[10] Sethi N, Narayanan V, Saaid R, et al. Prevalence, risk factors, and adverse outcomes of bacterial vaginosis among pregnant women: a systematic review. BMC Pregnancy Childbirth. 2025;25(1):40. Published 2025 Jan 20. doi:10.1186/s12884-025-07144-8

[11] Trabert B, Misra DP. Risk factors for bacterial vaginosis during pregnancy among African American women. Am J Obstet Gynecol. 2007;197(5):477.e1-477.e4778. doi:10.1016/j.ajog.2007.03.085

[12] Joyisa N, Moodley D, Nkosi T, et al. Asymptomatic Bacterial Vaginosis in Pregnancy and Missed Opportunities for Treatment: A Cross-Sectional Observational Study. Infect Dis Obstet Gynecol. 2019;2019:7808179. Published 2019 May 2. doi:10.1155/2019/7808179

[13] Mayo Clinic Staff. Sexually transmitted disease (STD) symptoms. Mayo Clinic. Updated May 5, 2022. Accessed March 2026.

[14] Yefet E, Mirin D, Massalha M, Alter A, Nachum Z. Screening for and Treatment of Bacterial Vaginosis Reduced Preterm Delivery in High-Risk Pregnant Women: A Systematic Review and Meta-Analysis. Gynecol Obstet Invest. 2025;90(4):353-362. doi:10.1159/000543502

[15] McDonald H, Brocklehurst P, Parsons J, Vigneswaran R. Antibiotics for treating bacterial vaginosis in pregnancy. Cochrane Database Syst Rev. 2003;(2):CD000262. doi:10.1002/14651858.CD000262

[16] Weir CB, Le JK. Metronidazole. [Updated 2023 Jun 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-.

[17] MotherToBaby | Fact Sheets [Internet]. Brentwood (TN): Organization of Teratology Information Specialists (OTIS); 1994-. Clindamycin. 2023 Oct.

[18] Hanson JM, McGregor JA, Hillier SL, et al. Metronidazole for bacterial vaginosis. A comparison of vaginal gel vs. oral therapy. J Reprod Med. 2000;45(11):889-896.

[19] Mayo Clinic Staff. Clindamycin (vaginal route). Mayo Clinic. Updated February 1, 2026. Accessed March 2026.

[20] Abbe C, Mitchell CM. Bacterial vaginosis: a review of approaches to treatment and prevention. Front Reprod Health. 2023;5:1100029. Published 2023 May 31. doi:10.3389/frph.2023.1100029

[21] Buchanan CL, Morris MA, Matlock D, Kempe A, Vemulakonda VM. Parental experience and understanding of parent-provider discussions of treatment for infants with ureteropelvic junction obstruction. PEC Innov. 2023;2:100142. Published 2023 Feb 21. doi:10.1016/j.pecinn.2023.100142

[22] McDonald HM, Brocklehurst P, Gordon A. Antibiotics for treating bacterial vaginosis in pregnancy. Cochrane Database Syst Rev. 2007;(1):CD000262. Published 2007 Jan 24. doi:10.1002/14651858.CD000262.pub3

[23] Muzny CA, Sobel JD. Understanding and Preventing Recurring Bacterial Vaginosis: Important Considerations for Clinicians. Int J Womens Health. 2023;15:1317-1325. Published 2023 Aug 9. doi:10.2147/IJWH.S383333

[24] Karpinets TV, Solley TN, Mikkelson MD, et al. Effect of Antibiotics on Gut and Vaginal Microbiomes Associated with Cervical Cancer Development in Mice. Cancer Prev Res (Phila). 2020;13(12):997-1006. doi:10.1158/1940-6207.CAPR-20-0103

[1] DuPont HL, Salge MMH. The Importance of a Healthy Microbiome in Pregnancy and Infancy and Microbiota Treatment to Reverse Dysbiosis for Improved Health. Antibiotics (Basel). 2023;12(11):1617. Published 2023 Nov 11. doi:10.3390/antibiotics12111617

[2] Muzny CA, Schwebke JR. Asymptomatic Bacterial Vaginosis: To Treat or Not to Treat?. Curr Infect Dis Rep. 2020;22(12):32. doi:10.1007/s11908-020-00740-z

[3] Carlson K, Mikes BA, Garg M. Bacterial Vaginosis. [Updated 2025 Nov 7]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-.

[4] Abou Chacra L, Ly C, Hammoud A, et al. Relationship between Bacterial Vaginosis and Sexually Transmitted Infections: Coincidence, Consequence or Co-Transmission?. Microorganisms. 2023;11(10):2470. Published 2023 Oct 1. doi:10.3390/microorganisms11102470

[5] Cleveland Clinic. Bacterial vaginosis (BV). Cleveland Clinic. Updated February 6, 2023. Accessed March 2026.

[6] Djogic LM, Cehic E, Hodzic H, Babic A, Sljivo B. Prevalence of Bacterial Vaginosis of Pregnant Women in the General Hospital Tesanj. Med Arch. 2025;79(3):194-198. doi:10.5455/medarh.2025.79.194-198

[7] Achondou AE, Fumoloh FF, Aseneck AC, Awah AR, Utokoro AM. Prevalence of bacterial vaginosis among sexually active women attending the CDC Central Clinic Tiko, South West Region, Cameroon. Afr J Infect Dis. 2016;10(2):96-101. doi:10.21010/ajid.v10i2.4

[8] Chen X, Lu Y, Chen T, Li R. The Female Vaginal Microbiome in Health and Bacterial Vaginosis. Front Cell Infect Microbiol. 2021;11:631972. Published 2021 Apr 7. doi:10.3389/fcimb.2021.631972

[9] Danjuma FY, Dashen MM, Ngene AC, Egbere OJ. Prevalence of bacterial vaginosis and its associated risk factors among women of reproductive age attending Jos University Teaching Hospital, Plateau State, Nigeria. GMS Hyg Infect Control. 2025;20:Doc51. Published 2025 Sep 22. doi:10.3205/dgkh000580

[10] Sethi N, Narayanan V, Saaid R, et al. Prevalence, risk factors, and adverse outcomes of bacterial vaginosis among pregnant women: a systematic review. BMC Pregnancy Childbirth. 2025;25(1):40. Published 2025 Jan 20. doi:10.1186/s12884-025-07144-8

[11] Trabert B, Misra DP. Risk factors for bacterial vaginosis during pregnancy among African American women. Am J Obstet Gynecol. 2007;197(5):477.e1-477.e4778. doi:10.1016/j.ajog.2007.03.085

[12] Joyisa N, Moodley D, Nkosi T, et al. Asymptomatic Bacterial Vaginosis in Pregnancy and Missed Opportunities for Treatment: A Cross-Sectional Observational Study. Infect Dis Obstet Gynecol. 2019;2019:7808179. Published 2019 May 2. doi:10.1155/2019/7808179

[13] Mayo Clinic Staff. Sexually transmitted disease (STD) symptoms. Mayo Clinic. Updated May 5, 2022. Accessed March 2026.

[14] Yefet E, Mirin D, Massalha M, Alter A, Nachum Z. Screening for and Treatment of Bacterial Vaginosis Reduced Preterm Delivery in High-Risk Pregnant Women: A Systematic Review and Meta-Analysis. Gynecol Obstet Invest. 2025;90(4):353-362. doi:10.1159/000543502

[15] McDonald H, Brocklehurst P, Parsons J, Vigneswaran R. Antibiotics for treating bacterial vaginosis in pregnancy. Cochrane Database Syst Rev. 2003;(2):CD000262. doi:10.1002/14651858.CD000262

[16] Weir CB, Le JK. Metronidazole. [Updated 2023 Jun 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-.

[17] MotherToBaby | Fact Sheets [Internet]. Brentwood (TN): Organization of Teratology Information Specialists (OTIS); 1994-. Clindamycin. 2023 Oct.

[18] Hanson JM, McGregor JA, Hillier SL, et al. Metronidazole for bacterial vaginosis. A comparison of vaginal gel vs. oral therapy. J Reprod Med. 2000;45(11):889-896.

[19] Mayo Clinic Staff. Clindamycin (vaginal route). Mayo Clinic. Updated February 1, 2026. Accessed March 2026.

[20] Abbe C, Mitchell CM. Bacterial vaginosis: a review of approaches to treatment and prevention. Front Reprod Health. 2023;5:1100029. Published 2023 May 31. doi:10.3389/frph.2023.1100029

[21] Buchanan CL, Morris MA, Matlock D, Kempe A, Vemulakonda VM. Parental experience and understanding of parent-provider discussions of treatment for infants with ureteropelvic junction obstruction. PEC Innov. 2023;2:100142. Published 2023 Feb 21. doi:10.1016/j.pecinn.2023.100142

[22] McDonald HM, Brocklehurst P, Gordon A. Antibiotics for treating bacterial vaginosis in pregnancy. Cochrane Database Syst Rev. 2007;(1):CD000262. Published 2007 Jan 24. doi:10.1002/14651858.CD000262.pub3

[23] Muzny CA, Sobel JD. Understanding and Preventing Recurring Bacterial Vaginosis: Important Considerations for Clinicians. Int J Womens Health. 2023;15:1317-1325. Published 2023 Aug 9. doi:10.2147/IJWH.S383333

[24] Karpinets TV, Solley TN, Mikkelson MD, et al. Effect of Antibiotics on Gut and Vaginal Microbiomes Associated with Cervical Cancer Development in Mice. Cancer Prev Res (Phila). 2020;13(12):997-1006. doi:10.1158/1940-6207.CAPR-20-0103